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Costs of secondary prevention of stroke by carotid endarterectomy
Carsten Hædersdal1, Mette Posborg Søndergaard, Tom Skyhøj Olsen
1Department of Clinical Physiology, Frederiksberg University Hospital, Frederiksberg, Denmark.
Insights
Preventing stroke with carotid endarterectomy (CEA) is costly. Performing CEA within two weeks of an ischemic event significantly reduces costs by approximately two-thirds.
Area of Science:
- Vascular Surgery
- Health Economics
- Neurology
Background:
- Carotid artery stenosis poses a significant stroke risk.
- Carotid endarterectomy (CEA) is a key intervention for preventing stroke in high-risk patients.
- Understanding the economic implications of CEA is crucial for healthcare resource allocation.
Purpose of the Study:
- To estimate the costs associated with preventing stroke via CEA in Denmark.
- To evaluate the cost-effectiveness of timely CEA intervention.
Main Methods:
- Cost analysis based on patients referred for carotid Doppler ultrasound (DUS) in Frederiksberg, Denmark.
- Inclusion of costs for patient identification, DUS, and CEA procedures.
- Data collected over an 18-month period (2008-2009).
Main Results:
- 372 patients with transient ischemic attack (TIA), stroke, or amaurosis fugax were referred for DUS.
- 12 patients had 50-70% stenosis, and 20 had >70% stenosis; 6 underwent CEA.
- The cost to prevent one recurrent stroke was EUR 207,675-333,918; this decreased to EUR 63,900-102,744 if CEA was performed within two weeks.
Conclusions:
- The costs of preventing stroke with CEA are substantial.
- Performing CEA within two weeks of an ischemic event can reduce costs by approximately two-thirds.
- Timely intervention is key to improving the cost-effectiveness of CEA for stroke prevention.
Background:
We estimated the costs to the Danish National Health Service of preventing stroke due to carotid artery stenosis by carotid endarterectomy (CEA), including costs of identifying patients, Doppler ultrasound (DUS) examination and CEA.
Methods:
Estimations are based on patients with stroke, transient ischemic attacks (TIA) or amaurosis fugax referred for carotid DUS in the municipality of Frederiksberg, Denmark (127,184 residents), within an 18-month period in 2008-2009.
Results:
In total, 372 patients with stroke (n = 194), TIA (n = 157) or amaurosis fugax (n = 21) were referred for DUS. We identified 12 patients with 50-70% stenosis and 20 patients with >70% stenosis. Six had CEA, all of whom had stenosis >70%. Waiting time from symptom to CEA was a median of 38 days. Costs of preventing 1 recurrent stroke in the study period [number needed to treat (NNT) = 13] was in the range of EUR 207,675-333,918. If CEA had been performed within 2 weeks after onset of symptoms (NNT = 4), costs would be in the range of EUR 63,900-102,744.
Conclusion:
Costs of preventing stroke by CEA were high. Substantial reductions of costs (by about 2/3) can be achieved if CEA is performed <2 weeks after the ischemic event.
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