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[Treatment of ectopic pregnancy using methotrexate]
Z Pilić1, N Juznić, A Radosavljević
1Ginekolosko akuserska Klinika klinickog centra, Beogradu.
Jugoslavenska Ginekologija I Perinatologija
|May 1, 1990
Summary
This study evaluated conservative treatment for ectopic pregnancy using methotrexate. The treatment was successful in 72.7% of patients, with surgery required for the remaining 27.3%.
Area of Science:
- Reproductive Medicine
- Gynecologic Oncology
Background:
- Ectopic pregnancy poses significant risks to maternal health.
- Conservative management is an alternative to surgical intervention for select cases.
Purpose of the Study:
- To assess the efficacy of methotrexate for ectopic pregnancy treatment.
- To evaluate outcomes in patients with intact ectopic pregnancy versus those with signs of tubal abortion.
Main Methods:
- Prospective study of 22 patients with ectopic pregnancy.
- Treatment involved local methotrexate injection into the gestational sac under ultrasound guidance.
- Systemic methotrexate and Citrovorum factor were administered to most patients.
Main Results:
- The conservative methotrexate treatment achieved a success rate of 72.7% (16 out of 22 patients).
- Six patients (27.3%) ultimately required surgical intervention.
- Treatment was successful even in some cases with hematocele, indicating tubal abortion.
Conclusions:
- Methotrexate is an effective conservative treatment for ectopic pregnancy.
- Patient selection, particularly regarding tubal abortion, is crucial for treatment success.