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Updated: May 21, 2026

Functionalization of Single-walled Carbon Nanotubes with Thermo-reversible Block Copolymers and Characterization by Small-angle Neutron Scattering
Published on: June 1, 2016
Characterization of a tamoxifen-tethered single-walled carbon nanotube conjugate by using NMR spectroscopy
Donna J Nelson1, Shagufta, Ravi Kumar
1Department of Chemistry and Biochemistry, University of Oklahoma, Norman, OK 73019, USA. djnelson@ou.edu
Abstract:
We report the synthesis and characterization of a tamoxifen-tethered single-walled carbon nanotube (SWCNT) conjugate, in which tamoxifen is covalently attached to the single-walled carbon nanotube via oxidation and esterification reactions for the first time. The functionalized SWCNT derivative was characterized by using spectroscopic techniques: IR, UV-vis, Raman, and (1)H NMR Spectroscopy. The attachment of the drug tamoxifen to SWCNTs is analogous to the gold conjugate, which provided an endocrine treatment for breast cancer.
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