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Post-cardiac arrest mortality is declining: a study of the US National Inpatient Sample 2001 to 2009
Jennifer E Fugate1, Waleed Brinjikji, Jay N Mandrekar
1Division of Critical Care Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Insights
US in-hospital cardiac arrest mortality rates significantly declined between 2001 and 2009. This study tracked over 1 million patients, revealing an 11.8% decrease in deaths for those hospitalized with cardiac arrest.
Area of Science:
- Cardiology
- Public Health
- Health Services Research
Background:
- Population-based mortality rates for cardiac arrest patients in the US have not been comprehensively studied over recent decades.
- Advances in postresuscitation care necessitate updated analyses of in-hospital outcomes.
- Understanding trends in cardiac arrest mortality is crucial for evaluating healthcare effectiveness.
Purpose of the Study:
- To determine the annual in-hospital mortality rates for patients hospitalized with cardiac arrest in the United States from 2001 to 2009.
- To analyze trends in cardiac arrest mortality over a nine-year period.
- To identify factors influencing in-hospital survival after cardiac arrest.
Main Methods:
- Utilized the 2001-2009 US National Inpatient Sample, a large national hospital discharge database.
- Identified patients with cardiac arrest using the International Classification of Diseases, 9th Edition, code 427.5.
- Analyzed in-hospital mortality rates, controlling for patient demographics (age, sex, race) and comorbidities.
Main Results:
- A total of 1,190,860 patients hospitalized with cardiac arrest were included in the study.
- The in-hospital mortality rate for cardiac arrest decreased annually from 69.6% in 2001 to 57.8% in 2009.
- This decline was observed across all analyzed subgroups, including variations in age, sex, race, and comorbidity status.
Conclusions:
- The in-hospital mortality rate for patients hospitalized with cardiac arrest in the United States experienced an 11.8% reduction between 2001 and 2009.
- Earlier years of hospitalization were a significant independent predictor of in-hospital death, even after adjusting for other factors.
- The findings indicate a positive trend in cardiac arrest survival within US hospitals during the study period.
Background:
Despite several advances in postresuscitation care over the past decade, population-based mortality rates for patients hospitalized with cardiac arrest in the United States have not been studied over this time period. The aim of this study was to determine the annual in-hospital mortality rates of patients with cardiac arrest from 2001 to 2009.
Methods And Results:
The US mortality rates for hospitalized patients with cardiac arrest were determined using the 2001 to 2009 US National Inpatient Sample, a national hospital discharge database. Using the International Classification of Diseases, 9(th) Edition, code 427.5, we identified patients hospitalized in the United States with cardiac arrest from 2001 to 2009. The main outcome measure was in-hospital mortality. A total of 1 190 860 patients were hospitalized with a diagnosis of cardiac arrest in the United States from 2001 to 2009. The in-hospital mortality rate decreased each year from 69.6% in 2001 to 57.8% in 2009. In multivariable analysis, when controlling for age, sex, race, and comorbidities, earlier year was a strong independent predictor of in-hospital death. The mortality rate declined across all analyzed subgroups, including sex, age, race, and stratification by comorbidity.
Conclusions:
The in-hospital mortality rate of patients hospitalized with cardiac arrest in the United States decreased by 11.8% from 2001 to 2009.
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