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Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
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Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

Bone health and multiple sclerosis.

Ruth Dobson1, Sreeram Ramagopalan, Gavin Giovannoni

  • 1Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University, UK. ruth.dobson@qmul.ac.uk

Multiple Sclerosis (Houndmills, Basingstoke, England)
|June 29, 2012
PubMed
Summary
This summary is machine-generated.

Multiple sclerosis (MS) patients face higher risks of low bone density and fractures. This review explores osteoporosis risks in MS and offers clinical practice suggestions.

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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
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Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
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Published on: September 9, 2022

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

Area of Science:

  • Neurology
  • Endocrinology
  • Orthopedics

Background:

  • Multiple sclerosis (MS) is associated with increased risks of low bone mineral density and fractures.
  • Osteoporosis is a significant cause of morbidity and mortality, disproportionately affecting individuals with MS.
  • Existing research highlights a link between MS and reduced bone mineral density.

Purpose of the Study:

  • To review the risks of low bone mineral density, osteoporosis, and fractures in people with MS.
  • To provide practical clinical suggestions for managing these bone health issues in MS patients.

Main Methods:

  • Topical review of existing studies.
  • Synthesis of evidence on MS and bone health.
  • Formulation of clinical practice recommendations.

Main Results:

  • Individuals with MS exhibit a higher prevalence of low bone mineral density and osteoporosis.
  • MS-related factors contribute to an elevated risk of fractures.
  • Clinical management strategies are crucial for mitigating bone loss and fracture risk in MS.

Conclusions:

  • Low bone mineral density and osteoporosis are prevalent concerns in multiple sclerosis.
  • Proactive clinical management is essential to address fracture risk in MS patients.
  • Further research and clinical guidelines are needed to optimize bone health outcomes for individuals with MS.