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A Case of Oral-contraceptive Related Ischemic Colitis in Young Woman
Choon Sik Seon1, Young Sook Park, Se Hwan Park
1Department of Internal Medicine, Eulji Medical Center, Eulji University College of Medicine, Seoul, Korea.
Insights
Ischemic colitis typically affects older adults. However, this case highlights oral contraceptives as a potential cause in young women, suggesting a need for broader consideration in diagnosis.
Area of Science:
- Gastroenterology
- Internal Medicine
- Pharmacology
Background:
- Ischemic colitis is commonly diagnosed in elderly patients.
- Established causes include cardiac dysfunction, hypovolemia, and certain medications like estrogen.
- Estrogen's role in ischemic colitis pathogenesis remains unclear.
Purpose of the Study:
- To report a rare case of ischemic colitis in a young woman.
- To investigate potential risk factors for ischemic colitis in younger demographics.
- To raise awareness regarding oral contraceptives as a possible etiology.
Main Methods:
- Case report presentation.
- Review of patient medical history.
- Literature review on estrogen-induced ischemic colitis.
Main Results:
- A 26-year-old woman presented with ischemic colitis.
- The patient had a history of long-term oral contraceptive use.
- No other significant risk factors for ischemic colitis were identified.
Conclusions:
- Oral contraceptives should be considered in the differential diagnosis of ischemic colitis in young women.
- Further research is needed to elucidate the mechanism of estrogen-induced ischemic colitis.
- This case broadens the understanding of risk factors for ischemic colitis beyond the elderly population.
Abstract:
Ischemic colitis is generally considered a disease of the elderly. The causes of ischemic colitis include low-flow states due to cardiac dysfunction or hypovolemia and certain medications including estrogen. Here we report a case of ischemic colitis in a 26-year-old woman. She had no specific medical history except taking oral-contraceptives for a long time. The mechanism of estrogen-induced ischemic colitis is not clearly understood. But we recommend that oral-contraceptives should be considered as a cause of ischemic colitis in young women.
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