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Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Related Experiment Video

Updated: May 20, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Published on: August 9, 2024

Metastatic synovial sarcoma to the orbit.

Edward J Wladis1, Martha G Farber, Anne G Nepo

  • 1Ophthalmic Plastic Surgery, Department of Ophthalmology, Lions Eye Institute, Albany Medical College, Albany, New York 12159, USA. tedwladis@gmail.com

Ophthalmic Plastic and Reconstructive Surgery
|June 30, 2012
PubMed
Summary

Metastatic synovial sarcoma is a rare cancer with a poor prognosis. This report details the second known case of synovial sarcoma spreading to the orbit, highlighting its rarity.

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Area of Science:

  • Oncology
  • Ophthalmology
  • Pathology

Background:

  • Synovial sarcoma is a rare soft tissue malignancy.
  • Metastatic disease in synovial sarcoma is associated with a poor prognosis.
  • Orbital involvement is an exceptionally rare presentation of metastatic synovial sarcoma.

Observation:

  • This report details the second documented case of metastatic synovial sarcoma to the orbit.
  • The case involves a patient with a known history of synovial sarcoma.

Findings:

  • Metastatic synovial sarcoma to the orbit is exceedingly rare.
  • Review of existing literature confirms the rarity of this condition.

Implications:

  • This case contributes to the limited understanding of orbital metastases from synovial sarcoma.
  • Highlights the importance of considering rare metastatic sites in cancer diagnosis.
  • Further research is needed to understand the behavior and treatment of orbital metastases.