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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

Imaging Biological Samples with Optical Microscopy

Imaging Biological Samples with Optical Microscopy

Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...

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Related Experiment Video

Updated: May 20, 2026

Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy

Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy

Published on: August 1, 2022

Biological imaging software tools.

Kevin W Eliceiri¹, Michael R Berthold, Ilya G Goldberg

¹Laboratory for Optical and Computational Instrumentation, University of Wisconsin at Madison, Madison, Wisconsin, USA. eliceiri@wisc.edu

|June 30, 2012

Summary

This summary is machine-generated.

Modern biological imaging relies heavily on software for data handling. This review explores computational steps, challenges, and open-source software solutions in bioimage informatics.

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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

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Whole-Brain Single-Cell Imaging and Analysis of Intact Neonatal Mouse Brains Using MRI, Tissue Clearing, and Light-Sheet Microscopy

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Published on: August 1, 2022

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

Area of Science:

Biology
Computer Science
Image Analysis

Background:

Imaging technologies are fundamental in modern biological research.
Recent advancements in optical technology offer unprecedented capabilities.
Software is crucial for managing and analyzing complex biological imaging data.

Purpose of the Study:

To review computational steps in bioimage informatics.
To identify challenges faced by biologists with digital imaging data.
To assess the current landscape of bioimage informatics software, emphasizing open-source solutions.

Main Methods:

Literature review of bioimage informatics.
Analysis of computational steps in biological image processing.
Evaluation of open-source software for bioimage analysis.

Main Results:

Identification of key computational stages in bioimage informatics.
Discussion of inherent challenges in biological image data handling.
Overview of available open-source software tools for bioimage analysis.

Conclusions:

Software development is essential for leveraging advanced biological imaging.
Open-source software plays a vital role in bioimage informatics.
Addressing computational challenges is key to advancing biological discovery through imaging.