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Updated: May 20, 2026

Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
Published on: January 15, 2018
Exocytosis of peptide functionalized gold nanoparticles in endothelial cells
Dorota Bartczak1, Simone Nitti, Timothy M Millar
1Institute for Life Sciences and Physics and Astronomy, Faculty of Physical and Applied Sciences, Highfield, University of Southampton, Southampton, UKSO17 1BJ.
Abstract:
We present the exocytosis profile of two types of peptide-coated nanoparticles, which have similar charge and size but different functionality. While one kind of particles appears to progressively exocytose, the other one has a more complex profile, suggesting that some of the particles are re-uptaken by the cells. Both types of particles retain their colloidal stability after exocytosis.

