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Related Experiment Video

Updated: May 20, 2026

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment
07:01

Working Memory Training for Older Participants: A Control Group Training Regimen and Initial Intellectual Functioning Assessment

Published on: September 20, 2020

Older adults with intellectual disability.

Amanda Sinai1, Ingrid Bohnen, Andre Strydom

  • 1Mental Health Sciences Unit, University College London, London, UK.

Current Opinion in Psychiatry
|June 30, 2012
PubMed
Summary
This summary is machine-generated.

Older adults with intellectual disability face increased risks of dementia and mental illness. While recent trials for dementia treatments were ineffective, they proved the feasibility of research in this population.

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Area of Science:

  • Gerontology
  • Intellectual Disability Research
  • Neuroscience

Background:

  • Increased life expectancy for individuals with intellectual disability (ID) leads to a growing population of older adults with ID.
  • This demographic experiences high rates of mental illness and is at significant risk for age-related cognitive disorders like dementia.

Purpose of the Study:

  • To review recent research on the health and well-being of older adults with intellectual disability.
  • To examine physical health, mental well-being, dementia, and end-of-life care in this population.

Main Methods:

  • Review of recent scientific literature focusing on older adults with intellectual disability.
  • Analysis of clinical trials, including those for dementia in people with Down syndrome.
  • Consideration of environmental, psychosocial, and end-of-life care issues.

Main Results:

  • Research highlights physical health issues impacting mental well-being and explores dementia characteristics in Down syndrome.
  • Clinical trials of memantine and antioxidants for dementia in Down syndrome showed short-term ineffectiveness.
  • Studies also addressed environmental, psychosocial factors, and end-of-life care.

Conclusions:

  • Effective management of mental and physical health, alongside social and environmental factors, is crucial for improving mental well-being in older adults with ID.
  • While recent medication trials for dementia were unsuccessful, they demonstrated the feasibility of conducting randomized controlled trials in older adults with intellectual disability.