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Updated: May 20, 2026
09:21
Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
Rare digital tumours: two case reports and mini review.
C W M Horner1, A Speller, T McBride
1Orthopaedic Department, New Cross Hospital, Wolverhampton, UK. christopherhorner@nhs.net
Summary
Rarer hand tumors, including digital myofibroma and aggressive digital papillary adenocarcinoma, require high suspicion for malignancy. Histological diagnosis is crucial for accurate treatment of hand masses, even those appearing benign.
Area of Science:
- Orthopedic Surgery
- Oncology
- Pathology
Background:
- Hand and finger masses are common in all age groups.
- While most masses are benign, rare aggressive tumors also occur.
- Accurate diagnosis is essential for effective management.
Observation:
- Presents two distinct cases: a digital myofibroma and an aggressive digital papillary adenocarcinoma.
- Highlights the importance of vigilance for malignant changes in long-standing, quiescent hand masses.
- Myofibromas, though benign, can cause significant bone destruction, mimicking aggressive lesions.
Findings:
- Digital myofibromas can exhibit concerning clinical features like bony destruction.
- Aggressive digital papillary adenocarcinoma presents a clinical appearance of benignity but possesses aggressive biological behavior.
- This tumor type shows a high propensity for local and distant metastasis.
Implications:
- Emphasizes the need for a high index of suspicion for malignancy in hand masses.
- Underscores the critical role of histological diagnosis for all resected hand masses.
- Informs clinical practice regarding the evaluation and management of rare hand tumors.
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