[Study of genetic markers in families of patients with tuberculosis]

The article deals with findings of the study of HLA-genotype influence on tuberculosis susceptibility in 26 families with tuberculosis patients. It was found that sensitivity to tuberculosis in the examined families is associated with HLA-DR2 antigen. Segregation analyses conducted in the families of patients with tuberculosis revealed a correlation between the sensitivity to tuberculosis and inheritance of certain HLA haplotypes from the affected parents to their children with tuberculosis.