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High reprint orders in medical journals and pharmaceutical industry funding: case-control study
Adam E Handel1, Sunil V Patel, Julia Pakpoor
1Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Insights
Pharmaceutical industry funding is linked to significantly higher reprint orders for medical journal articles. This association highlights potential influences on scientific dissemination and visibility.
Area of Science:
- Medical Journal Publishing
- Scientific Communication
Background:
- Reprint orders are a metric of article dissemination and impact.
- Understanding factors influencing reprint orders can shed light on scientific publishing dynamics.
Purpose of the Study:
- To investigate the association between study funding sources and design with high reprint orders in medical journals.
Main Methods:
- A case-control study design was employed.
- Top articles by reprint order volume from seven major medical journals (2002-2009) were analyzed.
- Articles were matched with contemporaneous control articles based on journal and publication period.
Main Results:
- Papers with high reprint orders were significantly more likely to receive funding from the pharmaceutical industry compared to control articles.
- Industry funding demonstrated a strong association (odds ratio 8.64) with high reprint orders.
- Mixed funding also showed a positive association (odds ratio 3.72).
Conclusions:
- Pharmaceutical industry funding is a significant predictor of high reprint order volumes for medical journal publications.
- This finding suggests a potential influence of industry funding on the dissemination of scientific research.
Objectives:
To assess the extent to which funding and study design are associated with high reprint orders.
Design:
Case-control study.
Setting:
Top articles by size of reprint orders in seven journals, 2002-09.
Participants:
Lancet, Lancet Neurology, Lancet Oncology (Lancet Group), BMJ, Gut, Heart, and Journal of Neurology, Neurosurgery & Psychiatry (BMJ Group) matched to contemporaneous articles not in the list of high reprint orders.
Main Outcome Measures:
Funding and design of randomised controlled trials or other study designs.
Results:
Median reprint orders for the seven journals ranged from 3000 to 126,350. Papers with high reprint orders were more likely to be funded by the pharmaceutical industry than were control papers (industry funding versus other or none: odds ratio 8.64, 95% confidence interval 5.09 to 14.68, and mixed funding versus other or none: 3.72, 2.43 to 5.70).
Conclusions:
Funding by the pharmaceutical industry is associated with high numbers of reprint orders.
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