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Related Experiment Video

Updated: May 20, 2026

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[Pure transgastric NOTES laparoscopy compared to classic laparoscopy].

V Veselý1, V Treska, J Molácek

  • 1Chirurgická klinika LF UK a FN v Plzni. vesely@fnplzen.cz

Rozhledy V Chirurgii : Mesicnik Ceskoslovenske Chirurgicke Spolecnosti
|July 4, 2012
PubMed
Summary

Natural orifice transluminal endoscopic surgery (NOTES) showed comparable results to laparoscopy in pigs, with fewer skin suture infections. Further technical development is needed for widespread clinical NOTES adoption.

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Area of Science:

  • Minimally Invasive Surgery
  • Surgical Innovation
  • Gastroenterology

Background:

  • Natural orifice transluminal endoscopic surgery (NOTES) offers a novel approach, avoiding skin incisions.
  • The Department of Surgery in Pilsen has utilized NOTES since 2008, beginning with hybrid techniques in animal models.
  • This study evaluates the pure transgastric NOTES method in a preclinical setting.

Purpose of the Study:

  • To compare the safety and efficacy of the transgastric pure NOTES technique against conventional laparoscopy.
  • To assess infectious complications and clinical outcomes in an animal model.

Main Methods:

  • A prospective study involving 15 domestic pigs undergoing transgastric pure NOTES via a double-channel endoscope.
  • Gastrotomy closure was achieved using OTSC clips.

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  • A control group of 15 pigs underwent standard laparoscopy, with both groups monitored for two weeks.

    • Main Results:

    • Transgastric pure NOTES demonstrated similar outcomes to laparoscopy.
    • Inflammation at the skin suture site occurred in 6 pigs (40%) undergoing laparoscopy.
    • No focal abdominal infections were observed in either group during follow-up or post-mortem examination.

    Conclusions:

    • The pure NOTES approach is technically challenging but feasible with current equipment.
    • Advancements in technical equipment are crucial for the successful clinical implementation of NOTES.