Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tangled Tail of Mechanically Interlocked Peptides.

Journal of the American Chemical Society·2026
Same author

STARD10 promotes progression of HER2+ breast cancer and intracellular lipid metabolism via the cAMP/PKA/CREB1 signaling axis.

Cancer biology & therapy·2026
Same author

High-intensity interval training identifies lipocalin 2 as a potential therapeutic target for hypothalamic neuroprotection in obesity.

Endokrynologia Polska·2026
Same author

Biosynthesis, Structure, and Antibiotic Properties of Gelatinamin A, a Triculamin-Like Lasso Peptide.

Chembiochem : a European journal of chemical biology·2026
Same author

Repositioning the Leader Peptide in Graspetide Biosynthesis.

Journal of the American Chemical Society·2026
Same author

Aspartimide Modification in RiPP Natural Products.

Biochemistry·2026

Related Experiment Video

Updated: May 20, 2026

Dynamic Light-Induced Protein Patterns at Model Membranes
07:10

Dynamic Light-Induced Protein Patterns at Model Membranes

Published on: February 23, 2024

Using light to covalently immobilize and pattern nanoparticles onto surfaces.

Ellane J Park1, Tina Wagenaar, Siyan Zhang

  • 1Department of Chemistry, Columbia University, 3000 Broadway Avenue, New York, New York 10027, United States.

Langmuir : the ACS Journal of Surfaces and Colloids
|July 4, 2012
PubMed
Summary

This study introduces a novel method for covalently attaching nanoparticles to surfaces using UV light and phthalimide chemistry. This versatile technique allows for precise nanoparticle patterning for advanced optical, electronic, and biological applications.

More Related Videos

A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates
08:09

A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates

Published on: May 9, 2014

Light-Induced Molecular Adsorption of Proteins Using the PRIMO System for Micro-Patterning to Study Cell Responses to Extracellular Matrix Proteins
09:49

Light-Induced Molecular Adsorption of Proteins Using the PRIMO System for Micro-Patterning to Study Cell Responses to Extracellular Matrix Proteins

Published on: October 11, 2019

Related Experiment Videos

Last Updated: May 20, 2026

Dynamic Light-Induced Protein Patterns at Model Membranes
07:10

Dynamic Light-Induced Protein Patterns at Model Membranes

Published on: February 23, 2024

A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates
08:09

A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates

Published on: May 9, 2014

Light-Induced Molecular Adsorption of Proteins Using the PRIMO System for Micro-Patterning to Study Cell Responses to Extracellular Matrix Proteins
09:49

Light-Induced Molecular Adsorption of Proteins Using the PRIMO System for Micro-Patterning to Study Cell Responses to Extracellular Matrix Proteins

Published on: October 11, 2019

Area of Science:

  • Materials Science
  • Nanotechnology
  • Surface Chemistry

Background:

  • Nanoparticles offer unique size-dependent properties for integration into various systems.
  • Current methods for nanoparticle immobilization often lack versatility and precise patterning capabilities.

Purpose of the Study:

  • To develop a universal and controllable method for covalent nanoparticle immobilization.
  • To enable precise patterning of nanoparticles on diverse substrates.

Main Methods:

  • Utilizing photoactive, phthalimide-functionalized self-assembled monolayers on substrates.
  • Employing UV radiation to initiate radical-based photografting of nanoparticles.
  • Applying masking techniques for controlled nanoparticle deposition and patterning.

Main Results:

  • Successfully demonstrated covalent immobilization of polymer nanoparticles onto glass and silicon substrates.
  • Achieved patterned deposition of nanoparticles confined to illuminated regions.
  • Characterized grafted films using atomic force microscopy and X-ray photoelectron spectroscopy.

Conclusions:

  • The developed photografting approach offers a versatile and effective strategy for nanoparticle integration.
  • This method facilitates the creation of patterned nanoparticle assemblies for advanced applications.
  • The technique is adaptable for various nanoparticle types and substrates.