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Updated: May 20, 2026

Evaluation of Left Ventricular Structure and Function using 3D Echocardiography
Published on: October 28, 2020
Does the routine echocardiographic exam have a role in the detection and evaluation of cholelithiasis and gallbladder
David D Daly1, Haytham El-Shurafa, Navin C Nanda
1Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA.
Insights
Routine echocardiography can detect gallstones (cholelithiasis). Three-dimensional echocardiography offers enhanced gallbladder visualization and stone analysis, improving upon traditional methods for diagnosing this common condition.
Area of Science:
- Cardiology
- Gastroenterology
- Medical Imaging
Background:
- Cholelithiasis (gallstones) is prevalent, often asymptomatic, but can lead to severe complications like cholecystitis, gallbladder perforation, and cancer.
- Routine transthoracic echocardiography is commonly performed for cardiac assessments.
Observation:
- Three cases of cholelithiasis were identified during routine transthoracic echocardiography.
- Echocardiography detected gallstones, prompting further three-dimensional (3D) echocardiographic evaluation.
Findings:
- 3D echocardiography provided comprehensive gallbladder assessment, including shape, size, wall thickening, and detailed 3D stone measurement and composition.
- 3D echocardiography minimized shadowing from calcifications and enabled full gallbladder examination via sequential slicing, overcoming limitations of 2D imaging.
Implications:
- Routine echocardiography demonstrates utility in detecting cholelithiasis.
- 3D echocardiography offers incremental diagnostic value over 2D echocardiography for gallbladder and gallstone evaluation, aiding radiologists in abdominal ultrasound interpretation.
Abstract:
Cholelithiasis is a very common disease in the United States. Most cases remain asymptomatic but a fraction of these patients can develop serious complications such as cholecystitis which may lead to gallbladder perforation and gallbladder cancer which is much less common. Here, we present three cases of cholelithiasis where transthoracic echocardiography was performed routinely. In each case, echocardiography detected cholelithiasis which prompted three-dimensional (3D) echocardiographic evaluation. Three-dimensional echocardiography allowed for more comprehensive examination of the gallbladder shape, size, and wall thickening and the measurement and composition of the stones in three dimensions, measurement of stone volumes, and minimized shadowing produced by stone calcifications. These cases suggest that routine echocardiography has value in detecting gallstones and that 3D echocardiography has incremental value over two-dimensional echocardiography due to pyramidal data sets which allow sequential slicing through the gallbladder and full gallbladder examination without a technologist who is trained in gallbladder imaging. These pyramidal data sets can be further viewed and cropped by a radiologist specialized in abdominal ultrasound.
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