Related Experiment Video
Updated: May 20, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Reticulated lesion as an early diagnostic sign for giant cell arteritis
Nicholas C Uffelmann1, Jessica Kozel, Sofia B Chaudhry
1Department of Dermatology, Saint Louis University, Saint Louis, Missouri, USA.
Abstract:
We report a case of giant cell arteritis (GCA) in an elderly woman. The patient presented to her dermatologist with a reticulated, purpuric patch on her frontal-temporal scalp and forehead that was associated with unilateral head pain. A punch biopsy of the lesion was suspicious for GCA, which was later confirmed by temporal artery biopsy. This case highlights a potential early cutaneous finding of GCA that may aid the clinician in the diagnosis before more severe complications occur.
Related Concept Videos
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Endocarditis II: Clinical Features of Infective Endocarditis
Rheumatic Heart Disease I: Introduction
