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[Recurrent gelastic syncopes].

H El Otmani1, F Moutaouakil, H Fadel

  • 1Service de neurologie, CHU Ibn-Rochd, Casablanca, Maroc; Service de neurologie, hôpital Al-Kortobi, Tanger, Maroc.

La Revue De Medecine Interne
|July 4, 2012
PubMed
Summary
This summary is machine-generated.

Gelastic syncope, or laughter-induced syncope, is a rare condition. This case study shows that propranolol effectively prevents these syncopal episodes triggered by laughter.

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Area of Science:

  • Neurology
  • Cardiology

Background:

  • Laughter-induced syncope, also known as gelastic syncope, is an uncommon and underrecognized condition.
  • This report details an additional case of this rare phenomenon.

Observation:

  • A 65-year-old male experienced four episodes of loss of consciousness exclusively triggered by laughter.
  • No significant past medical history, including diabetes or heart disease, was noted.
  • Neurological and cardiac examinations, along with extensive paraclinical investigations, were unremarkable.

Findings:

  • Laughter-induced syncope is hypothesized to be a form of vagal-mediated syncope, potentially linked to repetitive forced expiration similar to Valsalva maneuvers.
  • Propranolol treatment successfully prevented further syncopal attacks.

Implications:

  • This case highlights the effectiveness of propranolol in managing laughter-induced syncope.
  • It underscores the importance of considering gelastic syncope in the differential diagnosis of recurrent syncope, distinguishing it from conditions like gelastic atonic seizures and cataplexy.