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Updated: May 20, 2026

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In Vivo Functional Assessment of Rat Masseter Muscle Following Surgical Creation of a Volumetric Muscle Loss (VML) Injury
Published on: November 15, 2024
Muscle-only intra-oral mucosal defect reconstruction
D B Syme1, R Shayan, D Grinsell
1Department of Plastic Surgery, Reconstructive Plastic Surgery Unit, St Vincent's Hospital Melbourne, Fitzroy, Victoria 3065, Australia. david.syme@petermac.org
Summary
Muscle-only flaps effectively reconstruct oral mucosal defects after cancer surgery, restoring continuity and function. This approach offers a viable alternative for oral reconstruction, improving patient outcomes.
Area of Science:
- Oral and Maxillofacial Surgery
- Surgical Oncology
- Reconstructive Microsurgery
Background:
- Oral mucosal defects after oncologic resection require functional and cosmetic restoration.
- Current reconstruction often uses fasciocutaneous or myocutaneous flaps.
- Non-epithelial reconstructive techniques are less commonly reported.
Purpose of the Study:
- To evaluate the efficacy of muscle-only flaps for reconstructing medium to large oral mucosal defects.
- To assess the functional and aesthetic outcomes of this reconstructive approach.
Main Methods:
- A large series of patients undergoing oral defect reconstruction using muscle-only flaps was analyzed.
- Surgical techniques and patient outcomes were retrospectively reviewed.
Main Results:
- Muscle-only flaps demonstrated effectiveness in reconstructing intra-oral mucosal defects.
- This method achieved mucosal continuity, prevented salivary leaks, and ensured predictable healing.
Conclusions:
- Mucosalised muscle flaps represent an effective additional method for intra-oral mucosal defect reconstruction.
- This technique addresses reconstructive challenges in oncologic oral surgery.