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Related Experiment Video

Updated: May 20, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
07:27

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Published on: July 18, 2014

Congenital complete heart block: single tertiary centre experience.

Jennifer Yan1, Suraj K Varma, Atul Malhotra

  • 1Monash Newborn, Melbourne, Australia.

Heart, Lung & Circulation
|July 4, 2012
PubMed
Summary

Congenital complete heart block (CCHB) is a rare but serious condition in newborns. Most infants with CCHB require pacemakers, but outcomes are generally good with appropriate management.

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Area of Science:

  • Pediatric Cardiology
  • Neonatology
  • Congenital Heart Disease

Background:

  • Congenital complete heart block (CCHB) is an uncommon condition impacting neonatal health.
  • CCHB contributes to neonatal morbidity and mortality, necessitating further study.

Purpose of the Study:

  • To investigate the characteristics and outcomes of infants diagnosed with CCHB.
  • To determine the indications and timing for pacemaker insertion in these infants.

Main Methods:

  • Retrospective review of infants with CCHB over 20 years.
  • Analysis of patient demographics, maternal factors (e.g., SLE antibodies), cardiac anomalies (e.g., cCTGA), and pacemaker implantation data.

Main Results:

  • Fifteen infants with CCHB were identified; 53% had maternal SLE antibodies.
  • Eighty-seven percent of patients required pacemaker insertion, with a median age of six months.
  • Most patients maintained good systemic ventricular function, and one death occurred unrelated to CCHB.

Conclusions:

  • Congenital complete heart block is a significant neonatal condition.
  • While many infants require pacemakers, the long-term outcomes for CCHB patients are favorable.
  • Effective management, including timely pacemaker implantation, leads to good prognosis.