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Updated: May 20, 2026

Intraoperative Ultrasound in Spinal Surgery
Published on: August 17, 2022
Epidural inflammatory pseudotumor in the thoracic spine in a patient with polymyalgia rheumatica
Satoshi Kato1, Hideki Murakami, Satoru Demura
1Department of Orthopaedic Surgery, Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa 920-8641, Japan. skato323@gmail.com
Background Context:
Only six previous cases of epidural inflammatory psedotumor in the spine have been reported. None of them were seen in the course of polymyalgia rheumatica (PMR).
Purpose:
To describe a rare case of epidural inflammatory pseudotumor in the thoracic spine in a patient with PMR.
Study Design:
Case report.
Methods:
A 63-year-old man had a 6-year history of PMR treated with prednisone and cyclosporine. He presented with gait disturbance. Magnetic resonance imaging on the 12th day after the onset of the symptoms showed spinal cord compression caused by a posterior epidural mass at the T5-T6 level.
Results:
The patient underwent a T5-T6 laminectomy and a total excision of the mass, which involved the ligament flavum and epidural adipose tissue and firmly attached to the dura mater. Histopathologic examination revealed severe lymphoplasmacytic infiltration with fibrosis in the entire specimen and no evidence of hematomas or tumorous lesions. After surgery, the patient's neurologic symptoms disappeared immediately. Two years after surgery, the patient is neurologically normal and has not had a recurrence.
Conclusions:
This report identifies a rare case of epidural inflammatory pseudotumor in the thoracic spine in a patient with PMR.
Insights
This case report details a rare spinal epidural inflammatory pseudotumor in a polymyalgia rheumatica (PMR) patient. Surgical removal resolved the compression and neurological symptoms, with no recurrence.
Area of Science:
- Neurology
- Rheumatology
- Spinal Surgery
Background:
- Epidural inflammatory pseudotumors are exceptionally rare spinal lesions.
- Polymyalgia rheumatica (PMR) is an inflammatory condition typically affecting the elderly.
- No prior cases linked spinal epidural inflammatory pseudotumors to PMR.
Observation:
- A 63-year-old male with a history of PMR presented with gait disturbance.
- MRI revealed a posterior epidural mass at T5-T6 causing spinal cord compression.
- The mass involved the ligamentum flavum and epidural fat, adhering to the dura.
Findings:
- Histopathology showed lymphoplasmacytic infiltration and fibrosis, excluding tumor or hematoma.
- Surgical excision via laminectomy was performed.
- Immediate resolution of neurological deficits occurred post-surgery.
Implications:
- This case highlights a novel association between PMR and spinal epidural inflammatory pseudotumor.
- Early diagnosis and surgical intervention are crucial for favorable outcomes.
- Further research may elucidate the pathogenesis of this rare condition in PMR patients.
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