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The U.S. Environmental Protection Agency's risk assessment guidelines.
1U.S. Environmental Protection Agency Office of Health, Environmental Assessment Environmental Criteria and Assessment Office, Research Triangle Park, North Carolina.
Toxicology and Industrial Health
|October 1, 1990
Summary
The U.S. Environmental Protection Agency (EPA) developed risk assessment guidelines based on the U.S. National Academy of Sciences (NAS) framework. These guidelines ensure consistent, high-quality risk assessment across the agency.
Area of Science:
- Environmental Science
- Toxicology
- Risk Assessment
Background:
- Established in 1983, the U.S. National Academy of Sciences (NAS) proposed a comprehensive framework for governmental risk assessment and management.
- The U.S. Environmental Protection Agency (EPA) adopted this framework to guide its scientific and regulatory activities.
Framework:
- The EPA's risk assessment guidelines are organized around the NAS scheme.
- Key areas covered include exposure estimation, chemical mixtures, mutagenicity, developmental toxicity, and carcinogenicity.
Implementation:
- These guidelines were developed to ensure high technical quality and consistent application of risk assessment methodologies agency-wide.
- The paper details the historical evolution of these guidelines and their practical application within the EPA.
Implications:
- The document outlines each of the five core guidelines and discusses anticipated revisions.
- It also presents related assessment activities and emerging subject areas within environmental health and safety.