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Expansion of Human Peripheral Blood γδ T Cells using Zoledronate
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Effects of zoledronate on two- and three-dimensional osteoblast cultures

F Thibaut1, P Pellen-Mussi, F Pérez

  • 1Pôle d’Odontologie et de Chirurgie Buccale, UF de Chirurgie et Pathologie Buccales, Centre Hospitalier Universitaire, Rennes, France. flora.thibaut@univ-rennes1.fr

Bulletin Du Groupement International Pour La Recherche Scientifique En Stomatologie & Odontologie
|July 4, 2012
PubMed
Abstract

No abstract available in PubMed .

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Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...

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