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Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Related Experiment Video

Updated: May 20, 2026

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

[Dermatofibroma or melanoma?].

A Blum¹, R Hofmann-Wellenhof

¹a.blum@derma.de

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

|July 4, 2012

Summary

This summary is machine-generated.

Dermatoscopy revealed dermatofibroma-like features in three patients. The unique pattern, featuring peripheral hyperpigmentation and central hypopigmentation, necessitates considering melanoma in the differential diagnosis.

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Area of Science:

Dermatology
Dermoscopy
Oncology

Background:

Dermatofibromas are common benign skin tumors.
Dermoscopy is a non-invasive imaging technique crucial for skin lesion evaluation.
Accurate diagnosis of skin lesions is vital to exclude malignancy.

Observation:

Three patients presented with multiple, side-by-side skin lesions on their back.
Dermoscopic examination showed features resembling dermatofibromas in these lesions.
A distinct pattern of peripheral postinflammatory hyperpigmentation surrounding central scar-like hypopigmentation was noted.

Findings:

The observed dermoscopic pattern mimicked multiple dermatofibromas.
The presence of specific features, namely peripheral hyperpigmentation and central hypopigmentation, is highlighted.
This unique presentation requires careful consideration in the diagnostic process.

Implications:

The findings underscore the importance of considering melanoma in the differential diagnosis of lesions with these specific dermoscopic features.
This case series emphasizes the need for thorough evaluation of atypical presentations.
Improved diagnostic accuracy for challenging skin lesions can be achieved through detailed dermoscopic analysis.