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Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
Helicobacter pylori and infantile colic
1Department of Pediatrics, Al-Azhar University, Cairo, Egypt. abdelrazak_ali@yahoo.com
Archives of Pediatrics & Adolescent Medicine
|July 4, 2012
Summary
Helicobacter pylori (H pylori) infection is significantly associated with infantile colic. This finding suggests H pylori may be a contributing factor to colic in infants.
Area of Science:
- Pediatrics
- Microbiology
- Gastroenterology
Background:
- Infantile colic is a common condition in infants characterized by unexplained crying and fussiness.
- The etiology of infantile colic remains largely unknown, with various factors proposed.
Purpose of the Study:
- To investigate the potential association between Helicobacter pylori (H pylori) infection and infantile colic.
- To determine if H pylori is a causative factor in infantile colic.
Main Methods:
- A case-control study was conducted involving 55 infants diagnosed with infantile colic and 30 healthy controls.
- Participants were recruited from a tertiary hospital in rural Gizan, Saudi Arabia.
- Helicobacter pylori infection was identified using stool antigen testing.
Main Results:
- A high prevalence of H pylori infection was observed in infants with colic (81.8%) compared to healthy controls (23.3%).
- The odds ratio for H pylori infection in colicky infants was 15.3 (95% CI, 17.9-29.8), indicating a strong association.
Conclusions:
- Helicobacter pylori infection is significantly associated with infantile colic.
- The findings suggest that H pylori may play a role in the development of infantile colic.
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