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Acute myelopathy with normal imaging.

Neil R Holland¹

¹Neuroscience Institute, Monmouth Medical Center, Long Branch, NJ 07764, USA. nholland@neurologyspecialists.org

Journal of Child Neurology

|July 4, 2012

Summary

This summary is machine-generated.

A young woman experienced rapid paralysis and breathing difficulties, initially suspected as myelopathy. However, follow-up imaging revealed cervical cord changes, suggesting an alternative diagnosis after Guillain-Barré syndrome treatment.

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Area of Science:

Neurology
Neuroimmunology
Spinal Cord Imaging

Background:

Guillain-Barré syndrome (GBS) is an autoimmune disorder affecting peripheral nerves.
Rapidly progressive neurological deficits can mimic other spinal cord pathologies.
Accurate diagnosis is crucial for appropriate management of acute neurological emergencies.

Observation:

A 17-year-old female presented with quadriparesis and respiratory failure.
Initial investigations, including spinal imaging and cerebrospinal fluid analysis, did not support a diagnosis of myelopathy.
The patient had recently completed treatment for Guillain-Barré syndrome.

Findings:

Follow-up spinal imaging demonstrated interval expansion and enhancement of the cervical cord.
These findings suggest a progressive inflammatory or demyelinating process within the cervical spinal cord.
The evolution of imaging findings points towards a delayed or atypical manifestation potentially related to prior GBS.

Implications:

This case highlights the importance of serial imaging in diagnosing complex neurological conditions.
It underscores the potential for delayed or unusual presentations of inflammatory spinal cord disorders.
Recognizing such patterns is vital for differentiating from other causes of myelopathy and guiding treatment.