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Updated: May 20, 2026

Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
Published on: March 30, 2018
Membranoproliferative glomerulonephritis, mantle cell lymphoma infiltration, and acute kidney injury
Arkadiusz Lubas1, Andrzej Mróz, Jerzy Smoszna
1Department of Internal Medicine, Nephrology and Dialysotherapy, Military Institute of Medicine, ul. Szaserów 128, 04-141, Warsaw 44, Poland, alubas@wim.mil.pl.
Abstract:
Mantle cell lymphoma (MCL) is a rare aggressive lymphoid neoplasm occurring in about 3-7 % of non-Hodgkin lymphomas in the United States and Europe. Although lymphomas infiltrations are recognized in about half of post-mortem studies, in available literature we found only eight cases of mantle cell lymphoma with renal involvement. Five of them present MCL related glomerulonephritis, two show renal MCL infiltration with acute kidney injury and the last one describes MCL infiltration with acute tubulo-intrerstitial nephritis. We present the first case of a patient with the coexistence of renal mantle cell lymphoma infiltration, subacute membranoproliferative glomerulonephritis and acute kidney injury.
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