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Updated: Aug 14, 2026

Mouse Models of Periventricular Leukomalacia
Published on: May 18, 2010
[Problem of rehabilitation in perinatal lesions of the central nervous system]
Abstract:
Studies into the central nervous system (CNS) of fetuses, newborns, and infants with a history of intrauterine infection or intoxication suggest a possibility for development of viral, bacterial, and fungal encephalitis and encephalomyelitis in utero. These conditions may resolve antenatally or persist for a number of years after birth, and may give rise to autoimmune nonspecific inflammation which is self-sustained and thus of long duration. A complex rehabilitation therapy for these conditions employs immunomodulators, which significantly increases its efficacy. New techniques of massage and exercise were elaborated. A new method of local hypothermia has found wide application in various types of dysarthrosis in children with cerebral palsy.
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