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Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Substance Use Disorders Affecting Sleep01:24

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Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
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Drug Dependence01:17

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Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
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CNS stimulants, such as cocaine, amphetamines, and cannabinoids, have varying structures and mechanisms of action that lead to different therapeutic effects and side effects. Cocaine, with its molecular formula C17H21NO4, is a tropane alkaloid and a tertiary amino compound. It has two chemical forms: the hydrochloride salt and the "freebase." The former is in powder form, while the latter involves removing the hydrochloride salt to create a form that can be smoked. Cocaine exerts its effects by...
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[ADHD and addiction: a complicated liaison].

F Matthys1, S Tremmery, M Autrique

  • 1Algemeen Ziekenhuis St-Maarten, Mechelen en Free Clinic, een Medisch Sociaal Opvang Centrum voor druggebruikers, Antwerpen, Belgium. frieda.matthys@gmail.com

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Summary

Attention-Deficit/Hyperactivity Disorder (ADHD) significantly increases substance use disorder risk. Diagnosis and treatment of ADHD in addiction settings face obstacles, highlighting the need for better models.

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Area of Science:

  • Psychiatry and Neuroscience
  • Addiction Medicine

Context:

  • Attention-Deficit/Hyperactivity Disorder (ADHD) is prevalent in substance-abusing populations, being three times higher than in the general population.
  • ADHD is frequently overlooked and inadequately treated within addiction treatment centers.

Purpose:

  • To identify and describe the challenges hindering the accurate diagnosis and effective treatment of ADHD in individuals with substance use disorders.

Summary:

  • A historical analysis reveals parallel diagnostic evolution and societal biases toward ADHD and substance use disorders.
  • Neurobiological research on impulsivity and free will informs the understanding of these co-occurring conditions.
  • ADHD is increasingly acknowledged in addiction treatment, necessitating the development of explanatory frameworks.

Impact:

  • Improved recognition and management of ADHD in addiction treatment settings.
  • Enhanced understanding of the neurobiological underpinnings of co-occurring ADHD and substance use disorders.
  • Development of evidence-based models for integrated treatment approaches.