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Updated: May 20, 2026

An Ivor Lewis Esophagectomy Designed to Minimize Anastomotic Complications and Optimize Conduit Function
Published on: April 17, 2020
Is routine postoperative enteral feeding after oesophagectomy worthwhile?
George A C Wheble1, Ruth A Benson, Omar A Khan
1Department of Surgery, Queen Alexandra Hospital, Portsmouth, UK.
Immediate postoperative enteral feeding after oesophagectomy does not improve patient outcomes. Evidence from four randomized controlled trials shows no significant benefits in recovery or complications compared to standard oral feeding.
Area of Science:
- Surgical Oncology
- Gastroenterology
- Critical Care Medicine
Background:
- Oesophagectomy for cancer necessitates careful postoperative management.
- Early nutritional support is crucial for recovery, but optimal timing and method remain debated.
- Enteral feeding via jejunostomy or nasojejunostomy is an option for immediate postoperative nutrition.
Purpose of the Study:
- To evaluate the efficacy of immediate postoperative enteral feeding versus delayed oral feeding in patients undergoing oesophagectomy for cancer.
- To compare patient outcomes, including length of stay, complications, and mortality.
Main Methods:
- A systematic review of four randomized controlled trials (RCTs) was conducted.
- Studies compared immediate enteral feeding (jejunostomy or nasojejunostomy) with routine diet or delayed feeding.
- Outcomes assessed included anastomotic complications, mortality, length of stay, and catheter-related issues.
Main Results:
- No statistically significant differences were found in length of stay, anastomotic complications, or mortality between early enteral feeding and control groups.
- Some studies reported no clinical benefits of early enteral feeding, with one noting decreased pulmonary function in fed patients.
- Mortality was higher in one jejunostomy group, though not directly attributed to the feeding method.
Conclusions:
- Routine immediate postoperative enteral nutrition following oesophagectomy is feasible but does not confer significant clinical benefits.
- Current evidence does not support the routine use of early enteral feeding in patients without preoperative malnutrition.
- Further research may be needed to identify specific patient subgroups who might benefit from early enteral nutrition.
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