Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Anatomy of the Ear

Anatomy of the Ear

Auditory sensation, commonly called hearing, involves the transformation of sonic waves into neural impulses facilitated by the structures of the auditory organ. The prominent, flesh-like structure on the side of the head, called the auricle, directs sound waves towards the auditory canal. The auricle is often mislabeled as the pinna, a term more aligned with mobile structures like a feline's external ear. The auditory canal penetrates the cranium via the external auditory meatus of the...

The Cochlea

The Cochlea

The cochlea is a coiled structure in the inner ear that contains hair cells—the sensory receptors of the auditory system. Sound waves are transmitted to the cochlea by small bones attached to the eardrum called the ossicles, which vibrate the oval window that leads to the inner ear. This causes fluid in the chambers of the cochlea to move, vibrating the basilar membrane.

Hair Cells

Hair Cells

Hair cells are the sensory receptors of the auditory system—they transduce mechanical sound waves into electrical energy that the nervous system can understand. Hair cells are located in the organ of Corti within the cochlea of the inner ear, between the basilar and tectorial membranes. The actual sensory receptors are called inner hair cells. The outer hair cells serve other functions, such as sound amplification in the cochlea, and are not discussed in detail here.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Immortalized smooth muscle cells enhance in vitro vasculogenesis.

Research square·2026

Same author

Immortalized smooth muscle cells enhance in vitro vasculogenesis.

bioRxiv : the preprint server for biology·2026

Same author

A hybrid multiscale model for predicting CAR-T therapy outcomes in solid tumors.

Scientific reports·2026

Same author

Macrophages recruited by implanted fibrin gels promote regeneration of injured lymphatic vessels.

Scientific reports·2026

Same author

Volumetric mechanoplasticity couples melanoma drug tolerance to susceptibility to CD8<sup>+</sup> T cell killing.

bioRxiv : the preprint server for biology·2026

Same author

Overcoming impaired antigen presentation in tumor-draining lymph nodes facilitates immunotherapy.

Journal for immunotherapy of cancer·2025

Search research articles

Related Experiment Video

Updated: May 20, 2026

Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat

Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat

Published on: October 26, 2019

Rabbit ear chambers.

Rakesh K Jain, Lance L Munn, Dai Fukumura

Cold Spring Harbor Protocols

|July 4, 2012

Summary

This study details a surgical protocol for implanting transparent ear chambers in rabbits. This method enables long-term, noninvasive monitoring of angiogenesis in wound healing and tumor development.

Area of Science:

Surgical procedures
In vivo imaging
Angiogenesis research

Background:

Monitoring angiogenesis is crucial for understanding wound healing and tumor growth.
Existing methods for observing angiogenesis can be invasive or limited in duration.
New Zealand white rabbits are a suitable model for surgical implantation and observation.

Purpose of the Study:

To describe a protocol for surgically implanting transparent ear chambers in rabbits.
To enable continuous, noninvasive, long-term monitoring of angiogenesis.
To provide a method for tumor implantation within the chambers.

Main Methods:

Surgical implantation of transparent chambers into the ears of male New Zealand white rabbits.
Utilizing the chambers for continuous, noninvasive, long-term monitoring.

More Related Videos

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea

Published on: February 21, 2016

Related Experiment Videos

Last Updated: May 20, 2026

Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat

Simple Surgical Induction of Conductive Hearing Loss with Verification Using Otoscope Visualization and Behavioral Clap Startle Response in Rat

Published on: October 26, 2019

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea

Evaluation of Planar-Cell-Polarity Phenotypes in Ciliopathy Mouse Mutant Cochlea

Published on: February 21, 2016

Incorporating a specific method for tumor implantation.

Main Results:

The protocol allows for successful surgical implantation of transparent chambers.
The chambers facilitate noninvasive, long-term observation of angiogenesis.
The procedure is applicable to studying both wound healing and tumor angiogenesis.

Conclusions:

The described protocol provides a valuable tool for studying angiogenesis in vivo.
This method offers a noninvasive approach for long-term monitoring of biological processes.
The technique supports research in wound healing and tumor angiogenesis.