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Long-term outcome of children with oesophageal atresia type III

Céline Legrand1, Laurent Michaud, Julia Salleron

  • 1Reference Center for Congenital Malformations of the Esophagus, Department of Pediatrics, Jeanne de Flandre Children's Hospital, 1 place de Verdun, Lille, France.

Archives of Disease in Childhood
|July 4, 2012
PubMed

Insights

Patients with esophageal atresia type III (EA) often experience significant late sequelae, including digestive and respiratory issues, impacting their quality of life. Regular, multidisciplinary follow-up is crucial for managing these long-term complications.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Pulmonology

Background:

  • Esophageal atresia (EA) type III is a congenital condition requiring surgical intervention.
  • Long-term outcomes and quality of life in EA type III patients are not fully understood.
  • Late sequelae can significantly affect patient well-being.

Purpose of the Study:

  • To evaluate the long-term outcomes of patients with EA type III.
  • To identify the prevalence of late sequelae in this patient population.
  • To assess the quality of life in EA type III survivors.

Main Methods:

  • Retrospective case ascertainment and clinical assessment.
  • Data collection included demographics, associated abnormalities, GERD, symptoms, nutritional status, spirometry, and PedsQL 4.0.
  • 57 patients with EA type III were included in the analysis.

Main Results:

  • High rates of anastomotic stenosis (46%) and GERD symptoms (35%) were observed.
  • Respiratory symptoms, including chronic cough and dyspnea, were prevalent in 63% of patients.
  • Quality of life was lower than in healthy controls, particularly in those with prematurity, GERD, or barky cough.

Conclusions:

  • EA type III is associated with a high frequency of late sequelae.
  • Multidisciplinary and lifelong follow-up is essential for EA type III patients.
  • Addressing GERD and respiratory symptoms is key to improving long-term outcomes.
Abstract

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