Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Genetic Screens02:46

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing  genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which result in visible changes...
Quantifying and Rejecting Outliers: The Grubbs Test01:02

Quantifying and Rejecting Outliers: The Grubbs Test

Sometimes, a data set can have a recorded numerical observation that greatly  deviates from the rest of the data. Assuming that the data is normally distributed, a statistical method called the Grubbs test can be used to determine whether the observation is truly an outlier.  To perform a two-tailed Grubbs test, first, calculate the absolute difference between the outlier and the mean. Then, calculate the ratio between this difference and the standard deviation of the sample. This number is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Siderophore-producing bacteria reduce soil cadmium bioavailability and alleviate cadmium stress in alfalfa.

Ecotoxicology and environmental safety·2026
Same author

Cortico-basal oscillations index naturalistic movements during deep brain stimulation.

Brain : a journal of neurology·2025
Same author

Matrine in cancer therapy: antitumor mechanisms and nano-delivery strategies.

Frontiers in pharmacology·2025
Same author

High-dimensional Subgroup Regression Analysis.

Statistica Sinica·2025
Same author

Systematic investigation and validation of peanut genetic transformation via the pollen tube injection method.

Plant methods·2024
Same author

Statistical Inference for High-Dimensional Vector Autoregression with Measurement Error.

Statistica Sinica·2024
Same journal

Instrumental Variable Estimation of Marginal Structural Mean Models for Time-Varying Treatment.

Journal of the American Statistical Association·2026
Same journal

Semiparametric Joint Modeling for Survival Analysis with Longitudinal Covariates.

Journal of the American Statistical Association·2026
Same journal

Dimension Reduction for Large-Scale Federated Data: Statistical Rate and Asymptotic Inference.

Journal of the American Statistical Association·2026
Same journal

Facilitating Heterogeneous Effect Estimation via Statistically Efficient Categorical Modifiers.

Journal of the American Statistical Association·2026
Same journal

Nonparametric Density Estimation of a Long-Term Trend from Repeated Semicontinuous Data.

Journal of the American Statistical Association·2026
Same journal

Functional Integrative Bayesian Analysis of High-dimensional Multiplatform Clinicogenomic Data.

Journal of the American Statistical Association·2026
See all related articles

Related Experiment Video

Updated: May 20, 2026

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
07:35

Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

Published on: October 11, 2018

Model-Free Feature Screening for Ultrahigh Dimensional Data.

Liping Zhu, Lexin Li, Runze Li

    Journal of the American Statistical Association
    |July 4, 2012
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a new feature screening method for analyzing complex scientific data. The novel procedure consistently ranks and selects important predictors in ultrahigh-dimensional regressions, even with unknown model forms.

    More Related Videos

    Application of Unsupervised Multi-Omic Factor Analysis to Uncover Patterns of Variation and Molecular Processes Linked to Cardiovascular Disease
    08:51

    Application of Unsupervised Multi-Omic Factor Analysis to Uncover Patterns of Variation and Molecular Processes Linked to Cardiovascular Disease

    Published on: September 20, 2024

    Related Experiment Videos

    Last Updated: May 20, 2026

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances
    07:35

    Selecting Multiple Biomarker Subsets with Similarly Effective Binary Classification Performances

    Published on: October 11, 2018

    Application of Unsupervised Multi-Omic Factor Analysis to Uncover Patterns of Variation and Molecular Processes Linked to Cardiovascular Disease
    08:51

    Application of Unsupervised Multi-Omic Factor Analysis to Uncover Patterns of Variation and Molecular Processes Linked to Cardiovascular Disease

    Published on: September 20, 2024

    Area of Science:

    • Statistics
    • Data Science
    • Bioinformatics

    Background:

    • The increasing volume and complexity of scientific data necessitate advanced methods for feature analysis.
    • Feature ranking and screening are crucial for identifying relevant variables in large datasets.
    • Existing methods often require specific model assumptions, limiting their applicability.

    Purpose of the Study:

    • To propose a novel, unified feature screening procedure for ultrahigh-dimensional data.
    • To develop a method that is robust to various parametric and semiparametric models.
    • To enable consistent feature ranking and selection without prior model specification.

    Main Methods:

    • A unified model framework accommodating diverse regression models.
    • A novel feature screening procedure designed for ultrahigh-dimensional settings.
    • Demonstration of consistency in ranking and selection under exponential growth of predictors.

    Main Results:

    • The proposed procedure achieves consistent feature ranking, even with numerous predictors.
    • The method demonstrates consistency in feature selection.
    • The procedure is computationally efficient and simple to implement.

    Conclusions:

    • The novel feature screening procedure offers a powerful tool for modern scientific data analysis.
    • Its model-agnostic nature makes it suitable for ultrahigh-dimensional regressions with unknown structures.
    • The method shows strong empirical performance in simulations and real-world applications.