Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Difference from Background: Limit of Detection

Difference from Background: Limit of Detection

The limit of detection (LOD) is the smallest amount of analyte that can be distinguished from the background noise. The LOD value corresponds to the concentration at which the analyte signal is three times larger than the standard deviation of the blank signal. Below this value, the analyte signal cannot be differentiated from the background noise. It is calculated by dividing the calibration slope by 3 times the standard deviation of the blank signals.
The LOD indicates the presence or absence...

$Interference and Diffraction$ 02:18

Interference and Diffraction

Interference is a characteristic phenomenon exhibited by waves. When two electromagnetic waves interact with their peaks and troughs coinciding, a resulting wave with enhanced amplitude is produced. This is known as constructive interference. In this case, the two waves interacting are in phase with each other.

Atomic Absorption Spectroscopy: Interference

Atomic Absorption Spectroscopy: Interference

Interference leads to systematic error in atomic absorption (AA) measurements by enhancing or diminishing the analytical signal or the background. These interferences can be grouped into three main categories: spectral interference, chemical interference, and physical interference.
Spectral interference occurs when signals from other elements or molecules overlap with the analyte signal, falsely elevating or masking the analyte's absorbance. This interference can be corrected using Zeeman,...

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences

Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences

Inductively coupled plasma–mass spectrometry (ICP–MS) is a highly selective and sensitive technique for accurate elemental analysis. Though the analysis of ICP–MS mass spectra is comparatively straightforward, it is affected by spectroscopic and non-spectroscopic interferences. Spectroscopic interferences arise when the plasma contains ionic species with an m/z value the same as the analyte ion. Spectroscopic interference can be categorized as isobaric, polyatomic ions, and refractory oxide ion...

Atomic Emission Spectroscopy: Interference

Atomic Emission Spectroscopy: Interference

In atomic emission spectroscopy (AES), high-temperature atomizers excite a broad range of elements and molecules that generate complex emissions from sources such as oxides, hydroxides, and flame combustion products in the flame or plasma. Several strategies can be employed to minimize spectral interferences caused by overlapping emission lines or bands. These include increasing instrument resolution, choosing alternative emission lines, optimally placing the detector in low-background regions,...

Phase Contrast and Differential Interference Contrast Microscopy

Phase Contrast and Differential Interference Contrast Microscopy

Phase-Contrast Microscopes
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Molecular signatures of cortical expansion in the human foetal brain.

Nature communications·2024

Same author

Molecular signatures of cortical expansion in the human fetal brain.

bioRxiv : the preprint server for biology·2024

Same author

Non-negative data-driven mapping of structural connections with application to the neonatal brain.

NeuroImage·2020

Same author

Naturally occurring radioactivity in some Swedish concretes and their constituents - Assessment by using I-index and dose-model.

Journal of environmental radioactivity·2016

Same author

Exploration of the two-photon excitation spectrum of fluorescent dyes at wavelengths below the range of the Ti:Sapphire laser.

Journal of microscopy·2015

Same author

A simple but precise method for quantitative measurement of the quality of the laser focus in a scanning optical microscope.

Journal of microscopy·2015

Search research articles

Related Experiment Video

Updated: May 20, 2026

Implementation of a Reference Interferometer for Nanodetection

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

Balanced detection for interferometry with a noisy source.

E C Robinson¹, J Trägårdh, I D Lindsay

¹H.H. Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, United Kingdom.

The Review of Scientific Instruments

|July 5, 2012

Summary

This summary is machine-generated.

Researchers reduced noise in broadband supercontinuum sources using an auto-balancing technique. This enhances signal-to-noise ratio, enabling sensitive interferometric detection of low optical powers.

More Related Videos

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Published on: April 4, 2017

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

Published on: August 12, 2013

Related Experiment Videos

Last Updated: May 20, 2026

Implementation of a Reference Interferometer for Nanodetection

Implementation of a Reference Interferometer for Nanodetection

Published on: April 26, 2014

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Measurement of Quantum Interference in a Silicon Ring Resonator Photon Source

Published on: April 4, 2017

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

The Generation of Higher-order Laguerre-Gauss Optical Beams for High-precision Interferometry

Published on: August 12, 2013

Area of Science:

Optics and photonics
Nanotechnology
Metrology

Background:

Optical properties of nanostructures are contingent upon their size, shape, material composition, and surrounding environment.
Interferometry, utilizing a broadband light source, is a key technique for probing these optical characteristics.
A significant limitation in current interferometric measurements is the intrinsic noise associated with broadband supercontinuum sources, which compromises measurement sensitivity.

Purpose of the Study:

To introduce and evaluate an auto-balancing technique for mitigating noise in broadband supercontinuum sources.
To enhance the signal-to-noise ratio (SNR) of these sources for improved interferometric measurements.
To demonstrate the capability of detecting extremely low optical powers with high sensitivity.

Main Methods:

Implementation of an auto-balancing technique applied to a broadband supercontinuum light source.
Characterization of noise reduction achieved by the auto-balancing method.
Interferometric detection of low optical power signals using the noise-reduced source.

Main Results:

Demonstrated a substantial noise reduction of 41 dB in the broadband supercontinuum source.
Achieved a significant increase in the signal-to-noise ratio.
Enabled interferometric detection of optical powers as low as 0.01 picowatts (pW).
Confirmed successful detection within a short integration time of 5 milliseconds.

Conclusions:

The auto-balancing technique effectively suppresses noise in broadband supercontinuum sources.
This noise reduction significantly enhances measurement sensitivity, allowing for the detection of minute optical powers.
The method holds promise for advancing precision measurements in nanostructure characterization and other optical sensing applications.