On using 3D γ-analysis for IMRT and VMAT pretreatment plan QA
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Updated: May 20, 2026

Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System
Published on: April 11, 2018
Chuan Wu1, Kelly E Hosier, Kristen E Beck
1Radiation Oncology Centers (ROC), Radiological Associates of Sacramento (RAS), Sacramento, CA 95815, USA. wuc@radiological.com
Purpose:
To investigate using 3D γ analysis for IMRT and VMAT QA.
Methods:
We explored and studied 3D γ-analysis by comparing TPS computed and EPID back-projection reconstructed doses in patient's CT images. Two 3D γ quantities, γ(PTV) and γ(10), were proposed and studied for evaluating the QA results, and compared to 2D γ (MapCheck composite: γ(MC)).
Results:
It was found that when 3%(global)/3 mm criteria was used, all IMRT and 90% of VMAT plans passed QA with a γ pass rate ≥90%. A significant statistical correlation was observed between 3D and 2D γ-analysis results for IMRT QA if γ(10) and γ(MC) are concerned, but no significant relation is found between γ(PTV) and γ(MC).
Conclusions:
3D γ analysis based on EPID dose back-projection may provide a feasible tool for IMRT and VMAT pretreatment plan QA.
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