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Updated: May 20, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
Published on: September 30, 2021
Difficult clinical challenges in haemophilia: international experiential perspectives
Angela L Forsyth1, Paul Giangrande, Charles R M Hay
1RUSH Hemophilia and Thrombophilia Center, RUSH University Medical Center, Chicago, Illinois, USA.
Abstract:
Haemostasis management in people with haemophilia can present a range of challenges to physicians. Specific challenges that may be encountered relate to regimens for immune tolerance induction, use of central venous access devices, optimizing care of paediatric patients with inhibitors and improving outcomes in acquired haemophilia. There are also challenges related to performing surgery, and the establishment of specialist centres is valuable with regard to this. These challenges are considered in the light of available data, and with perspectives gained from the experience of experts treating patients around the world. Sharing this knowledge may help to improve patient management.
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