Related Experiment Video
Updated: May 20, 2026
05:22
Iris Fixation via External Pentagram Suturing
Published on: May 5, 2022
Isolated ocular cutaneous involvement in antiphospholipid syndrome
1University Hospital Leicester, Leicester, Leicester, UK. aneesanazreen@yahoo.co.uk
Orbit (Amsterdam, Netherlands)
|July 5, 2012
Summary
Antiphospholipid syndrome (APS) can present unusually, even with isolated ocular symptoms like swelling and non-healing ulcers. Early diagnosis of atypical APS is crucial for effective management.
Area of Science:
- Ophthalmology
- Rheumatology
- Immunology
Background:
- Antiphospholipid syndrome (APS) is characterized by thrombosis or pregnancy morbidity with antiphospholipid antibodies (aPL).
- Ocular and neuro-ophthalmic manifestations are recognized in APS, including retinal vascular occlusions and optic neuropathies.
Observation:
- A case of a 24-year-old male with recurrent periocular edema and a non-healing biopsy site ulcer is presented.
- This patient exhibited an isolated ocular presentation without systemic signs of APS or abnormal inflammatory markers.
Findings:
- The case highlights an unusual, isolated ocular manifestation of Antiphospholipid Syndrome (APS).
- Normal ocular examinations and inflammatory markers initially obscured the diagnosis.
Implications:
- Atypical presentations of APS, particularly isolated ocular findings, can pose diagnostic challenges.
- Increased awareness of unusual APS manifestations is necessary for timely diagnosis and treatment.
