Children diagnosed with type 1 diabetes: a randomized controlled trial comparing hospital versus home-based care

Irén Tiberg1, Steen Carlsson Katarina, Annelie Carlsson

  • 1Department of Health Sciences and The Swedish Institute for Health Sciences, Lund University, Lund, Sweden. iren.tiberg@med.lu.se

Insights

Hospital-based home care (HBHC) is as safe and effective as traditional hospital care for children with type 1 diabetes. This approach improves parental satisfaction and reduces healthcare resource use, offering a viable alternative for stable patients.

Area of Science:

  • Pediatric Endocrinology
  • Health Services Research
  • Diabetes Management

Background:

  • Type 1 diabetes management in children requires effective care strategies.
  • Hospital-based care is a standard approach, but alternatives are being explored.
  • Hospital-based home care (HBHC) offers specialist care in a home setting.

Purpose of the Study:

  • To compare the efficacy and safety of hospital-based care versus HBHC for children with newly diagnosed type 1 diabetes.
  • To evaluate metabolic control, family well-being, and healthcare resource utilization.

Main Methods:

  • A randomized controlled trial was conducted in Sweden with 60 children (aged 3-15 years).
  • Participants received initial hospital-based care, followed by randomization to either continued hospital care or HBHC.
  • Outcomes assessed at 6 months included metabolic control, family situation, and healthcare resource use.

Main Results:

  • Equivalence was observed between HBHC and hospital care regarding metabolic control and insulin dosage.
  • Parents in the HBHC group reported higher satisfaction and lower subsequent healthcare resource use.
  • Psychosocial distress at diagnosis correlated with resource use, not metabolic control.

Conclusions:

  • Hospital-based home care (HBHC) is a safe and effective alternative to hospital-based care for medically stable children with new-onset type 1 diabetes.
  • HBHC enhances parental satisfaction and optimizes healthcare resource utilization.
  • The findings support HBHC as a valuable care model in pediatric diabetes management.
Abstract

Related Concept Videos

Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Insulin: Dosing Regimen and Adverse Effects01:16

Insulin: Dosing Regimen and Adverse Effects

Insulin-replacement therapy usually includes both long-acting insulin (basal) and short-acting insulin (to cater to postprandial needs). In a diverse group of type 1 diabetes patients, the average daily insulin dose is typically 0.5-0.7 units/kg body weight. However, obese patients and pubertal adolescents may need more due to insulin resistance.
The basal dose constitutes about 40%-50% of the total daily dose, with the rest as premeal insulin. The mealtime insulin dose should mirror...
Type I Diabetes I: Introduction01:12

Type I Diabetes I: Introduction

Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1 diabetes is an...
Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Type I Diabetes III: Clinical Manifestations01:19

Type I Diabetes III: Clinical Manifestations

Type 1 diabetes mellitus typically presents with rapid-onset symptoms due to the body’s inability to utilize glucose in the absence of insulin. Since insulin is required for glucose uptake into cells, its deficiency leads to hyperglycemia and cellular energy deprivation, resulting in characteristic clinical features.Polyuria and PolydipsiaOne of the earliest, most prominent symptoms is polyuria (excessive urination). When blood glucose concentrations rise above the renal threshold, the kidneys...