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Inflammatory fibroid polyp. A case report and review of the literature

Piero Rossi1, Mauro Montuori, Valerio Balassone

  • 1Policlinico Tor Vergata, Roma, Italy. piero.rossi.box@alice.it

Annali Italiani Di Chirurgia
|July 5, 2012
PubMed
Abstract

Insights

Inflammatory fibroid polyps (IFPs) are rare benign gastrointestinal tumors. Diagnosis can be challenging, often requiring surgical excision for definitive treatment and to prevent recurrence.

Area of Science:

  • Gastroenterology
  • Surgical Pathology

Background:

  • Inflammatory fibroid polyps (IFPs) are rare mesenchymal neoplasms of the gastrointestinal tract, typically benign.
  • They are characterized by submucosal proliferation of vascularized fibromuscular tissue with eosinophilic infiltration.
  • While IFPs can occur anywhere in the GI tract, they are most common in the gastric antrum (70%).

Observation:

  • A case of a 71-year-old woman with non-specific symptoms like loss of appetite, nausea, and early satiety is presented.
  • A literature review identified 196 cases of IFPs between 1949 and 2011.
  • Endoscopic examination often reveals submucosal lesions, with biopsies frequently yielding non-diagnostic results.

Findings:

  • Clinical presentation of IFPs is heterogeneous, making diagnosis difficult.
  • Differential diagnosis includes eosinophilic gastroenteritis, GIST, inflammatory pseudotumor, hemangioendothelioma, and hemangiopericytoma.
  • Combined eco-endoscopic appearance and biopsies can suggest an IFP diagnosis.

Implications:

  • Despite being benign, IFPs often necessitate surgical excision with clear margins.
  • Incomplete excision is associated with a high rate of local recurrence.
  • Accurate diagnosis and complete surgical removal are crucial for managing IFPs and preventing recurrence.

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