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Plasmonic nanogap-enhanced Raman scattering using a resonant nanodome array.

Hsin-Yu Wu1, Charles J Choi, Brian T Cunningham

  • 1Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, 208 North Wright Street, Urbana, IL 61801, USA.

Small (Weinheim an Der Bergstrasse, Germany)
|July 5, 2012
PubMed
Summary

Plasmonic nanodome array (PNA) substrates offer sensitive surface-enhanced Raman scattering (SERS) detection. These cost-effective, flexible substrates achieve high enhancement factors for chemical and biological sensing.

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Area of Science:

  • Plasmonics
  • Nanotechnology
  • Spectroscopy

Background:

  • Plasmonic nanostructures are crucial for enhancing light-matter interactions.
  • Surface-enhanced Raman scattering (SERS) offers high sensitivity for molecular detection.
  • Developing cost-effective and scalable SERS substrates is essential for practical applications.

Purpose of the Study:

  • To investigate the optical properties and SERS performance of plasmonic nanodome array (PNA) substrates.
  • To evaluate the potential of PNAs for chemical and biological sensing applications.
  • To understand the relationship between PNA structure, localized surface plasmon resonance (LSPR), and SERS enhancement.

Main Methods:

  • Fabrication of PNA substrates using large-area nanoreplica moulding on flexible plastic.

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  • Characterization of optical properties through experimental measurements and numerical simulations.
  • Evaluation of SERS performance using gold-coated PNAs and detection of metabolites.

    • Main Results:

    • PNAs exhibit both radiative LSPR and non-radiative surface plasmon resonance (SPR).
    • High hot spot density (6.25 × 10^6 mm^-2) achieved with uniform fabrication.
    • Spatially averaged SERS enhancement factor (EF) of 8.51 × 10^7 for Au-coated PNAs.
    • Demonstrated reliable and reproducible SERS detection of metabolites at physiological concentrations.

    Conclusions:

    • PNAs are effective SERS substrates with significant enhancement factors.
    • The cost-effective fabrication method enables large-area applications.
    • PNAs show promise for sensitive and selective chemical and biological sensing.