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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of ¹⁸FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Cutaneous tuberculosis caused by isoniazid-resistant Mycobacterium tuberculosis.

Mehrnaz Asadi Gharabaghi¹

¹Department of Respiratory Medicine, Tehran University of Medical Sciences, Tehran, Iran. asadi_m@turns.ac.ir

BMJ Case Reports

|July 5, 2012

Summary

Cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis, particularly in individuals with healthy immune systems. This case highlights isoniazid-resistant Mycobacterium tuberculosis causing skin plaques in an immune-competent adult.

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Area of Science:

Dermatology
Infectious Diseases
Microbiology

Background:

Cutaneous tuberculosis (TB) is an uncommon manifestation of extrapulmonary TB.
It is particularly rare in immunocompetent individuals.
Tuberculosis can present with diverse dermatological symptoms.

Observation:

A case report of a 38-year-old male patient is presented.
The patient exhibited non-pruritic skin plaques.
Lesions were located on the buttock, inguinal area, and earlobe.

Findings:

The skin plaques were caused by Mycobacterium tuberculosis.
The causative strain of Mycobacterium tuberculosis was resistant to isoniazid.
This indicates a specific drug-resistant pattern in a cutaneous TB presentation.

Implications:

This case underscores the importance of considering cutaneous TB in immunocompetent patients with unexplained skin lesions.
Isoniazid resistance in cutaneous TB necessitates alternative treatment strategies.
Further research into the epidemiology and management of drug-resistant cutaneous TB is warranted.