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Analgesic and Anti-Inflammatory Activity of Pinus roxburghii Sarg
Dhirender Kaushik1, Ajay Kumar, Pawan Kaushik
1Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra 136 119, India.
Advances in Pharmacological Sciences
|July 5, 2012
Summary
Chir Pine (Pinus roxburghii) bark extract shows significant pain-relieving and anti-inflammatory effects in animal studies. This traditional herbal remedy holds potential for treating inflammatory disorders.
Area of Science:
- Phytochemistry
- Pharmacology
- Ethnomedicine
Background:
- Chir Pine (Pinus roxburghii) is a Himalayan pine species.
- Its oil is traditionally used in Indian herbal preparations for inflammatory conditions.
Purpose of the Study:
- To evaluate the analgesic and anti-inflammatory potential of Pinus roxburghii bark extract.
- To provide scientific validation for its traditional medicinal uses.
Main Methods:
- An alcoholic bark extract of Pinus roxburghii was prepared.
- Analgesic activity was assessed using acetic acid-induced writhing and tail immersion tests in mice.
- Anti-inflammatory effects were evaluated via carrageenan-induced paw edema and cotton pellet granuloma models in rats.
Main Results:
- The alcoholic bark extract of Pinus roxburghii exhibited significant dose-dependent analgesic activity.
- The extract also demonstrated notable anti-inflammatory effects in both acute and chronic models.
Conclusions:
- Pinus roxburghii bark extract possesses significant analgesic and anti-inflammatory properties.
- These findings support the traditional use of Chir Pine for managing pain and inflammation.
