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[1:1 pair matched case-control study on bladder cancer].

L Wang1

  • 1Institute of Epidemiology and Microbiology, Chinese Academy of Preventive Medicine, Beijing.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi
|December 1, 1990
PubMed
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This study identified key bladder cancer risk factors, including smoking, urinary disease history, and high meat consumption. Milk consumption showed a protective association, suggesting dietary influences on bladder cancer risk.

Area of Science:

  • Epidemiology
  • Oncology

Background:

  • Bladder cancer poses a significant public health challenge.
  • Identifying modifiable risk factors is crucial for prevention strategies.

Purpose of the Study:

  • To investigate the risk factors associated with bladder cancer.
  • To identify specific lifestyle, occupational, and historical factors contributing to bladder cancer development.

Main Methods:

  • A 1:1 pair-matched case-control study was conducted in Wuhan city in 1988.
  • 101 case-control pairs were matched on sex, age, and hospital.
  • Data collected through interviews covered health history, lifestyle, occupation, and family cancer history.

Main Results:

  • Bivariate analysis identified 10 factors associated with bladder cancer.

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  • Conditional logistic regression confirmed 5 significant risk factors.
  • Highest risks were linked to cigarette smoking, urinary disease history, occupational exposure to bladder cancer cases, and high monthly meat intake (>1.5 kg).
  • Milk consumption demonstrated a significant negative association, suggesting a protective effect.

    • Conclusions:

    • Cigarette smoking, certain occupational exposures, and dietary habits (high meat intake) are significant risk factors for bladder cancer.
    • Urinary disease history is a critical risk factor.
    • Milk consumption may offer a protective effect against bladder cancer.