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Cyclical vomiting syndrome in children: a prospective study

B R Drumm1, B Bourke, J Drummond

  • 1UCD School of Medicine and Medical Sciences, Dublin Academic Medical Centre, Dublin 7, Ireland.

Neurogastroenterology and Motility
|July 6, 2012
PubMed

Insights

Cyclical vomiting syndrome (CVS) in children often persists after diagnosis, but symptom frequency and severity decrease. Early diagnosis and family education are key to managing CVS and reducing medical service use.

Area of Science:

  • Pediatrics
  • Gastroenterology
  • Child Psychology

Background:

  • Cyclical vomiting syndrome (CVS) is a disorder characterized by severe nausea and vomiting episodes with symptom-free intervals.
  • It affects all age groups, with an incidence of 3.15 per 100,000 children annually.
  • The natural history and factors predicting symptom resolution in pediatric CVS require further evaluation.

Purpose of the Study:

  • To evaluate the natural history of cyclical vomiting syndrome in children.
  • To identify factors that predict symptom resolution in pediatric CVS cases.

Main Methods:

  • Thirty newly diagnosed children with CVS (mean age 9.15 years) were enrolled.
  • Follow-up interviews were conducted at 3, 6, and 9 months post-diagnosis.
  • Psychological assessments (CBCL) and quality of life scores (PedsQL) were utilized.

Main Results:

  • At 9 months, 77.3% of children continued to experience vomiting episodes.
  • Hospital admissions significantly decreased post-diagnosis (1/22 children) compared to the prior year (15/30 children).
  • Children with persistent vomiting showed poorer quality of life at diagnosis (P < 0.05).

Conclusions:

  • A prompt diagnosis and family education are crucial for managing pediatric CVS.
  • While many children continue to experience vomiting, symptom frequency and severity significantly reduce.
  • Medical service utilization markedly decreases following diagnosis and management.
Abstract

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