Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Low-dose exercise protects the heart against established myocardial infarction via IGF-1-upregulated CTRP9 in male mice.

MedComm·2023
Same author

Forkhead box O6 (FoxO6) promotes cardiac pathological remodeling and dysfunction by activating Kif15-TGF-β1 under aggravated afterload.

MedComm·2023
Same author

Evaluating the monogenic contribution and genotype-phenotype correlation in patients with isolated thoracic aortic aneurysm.

European journal of human genetics : EJHG·2021
Same author

Sex Differences of Clinical Presentation and Outcomes in Propensity-Matched Patients with Acute Type A Aortic Dissection.

The heart surgery forum·2021
Same author

Novel PGC-1<i>α</i>/ATF5 Axis Partly Activates UPR<sup>mt</sup> and Mediates Cardioprotective Role of Tetrahydrocurcumin in Pathological Cardiac Hypertrophy.

Oxidative medicine and cellular longevity·2021
Same author

Effectiveness of a novel, completely biomaterial valved pulmonary arterial conduit: An <i>in vivo</i> study.

Experimental and therapeutic medicine·2020
Same journal

Real-World Effectiveness and Tolerability of Sacubitril/Valsartan in Octogenarian Patients With Heart Failure: Results From the PARACHUTER Study.

The American journal of cardiology·2026
Same journal

ECG-Guided Conduction Pathways as a Lever to Shorten Post-TAVI Hospitalization.

The American journal of cardiology·2026
Same journal

Cystatin-C versus creatinine and kidney function in heart failure with preserved ejection fraction: a SOGALDI-PEF analysis.

The American journal of cardiology·2026
Same journal

Balloon-expandable versus Self-expanding Valves in Patients with Small Aortic Annuli Undergoing Transcatheter Aortic Valve Replacement.

The American journal of cardiology·2026
Same journal

Drug-Coated Balloons versus Drug-Eluting Stents following Coronary Atherectomy in Severely Calcified Lesions: A Systematic Review and Meta-Analysis.

The American journal of cardiology·2026
Same journal

Prehospital Statin Therapy and Outcomes in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

The American journal of cardiology·2026
See all related articles

Related Experiment Video

Updated: May 20, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Acute aortic dissection in China.

Yang Li1, Nan Yang, Weixun Duan

  • 1Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, China.

The American Journal of Cardiology
|July 6, 2012
PubMed
Summary
This summary is machine-generated.

This study analyzed acute aortic dissection (AAD) in China, revealing hypertension and chest pain as key risk factors. Outcomes varied significantly between Type A and Type B AAD, highlighting the need for tailored clinical approaches.

More Related Videos

Murine Model of Thoracic Aortic Dissection Induced by Oral &#946;-Aminopropionitrile and Subcutaneous Angiotensin II Infusion
05:31

Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion

Published on: May 16, 2025

Related Experiment Videos

Last Updated: May 20, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Murine Model of Thoracic Aortic Dissection Induced by Oral &#946;-Aminopropionitrile and Subcutaneous Angiotensin II Infusion
05:31

Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion

Published on: May 16, 2025

Area of Science:

  • Cardiovascular Medicine
  • Thoracic Surgery
  • Diagnostic Imaging

Background:

  • Acute aortic dissection (AAD) is a life-threatening condition with significant morbidity and mortality.
  • Limited data exists on the clinical profiles and outcomes of AAD specifically within the Chinese population.
  • Understanding regional variations in AAD is crucial for refining diagnostic and therapeutic strategies.

Purpose of the Study:

  • To retrospectively evaluate the clinical characteristics, treatment modalities, and in-hospital outcomes of patients with acute aortic dissection in China.
  • To identify predictive factors associated with increased in-hospital mortality in AAD patients.
  • To provide insights into the current management and outcomes of AAD in a large Chinese cohort.

Main Methods:

  • Retrospective analysis of 1,812 patients diagnosed with AAD between January 1, 2008, and December 31, 2011, across 19 major Chinese hospitals.
  • Data collection included patient demographics, clinical presentation, imaging findings, treatment interventions (surgical and endovascular), and in-hospital mortality.
  • Multivariate logistic regression analysis was employed to identify independent predictors of mortality.

Main Results:

  • The study included 1,812 patients (726 Type A, 1,086 Type B AAD) with a mean age of 51.1 years; 77.5% were male. Hypertension was prevalent.
  • Overall in-hospital mortality was 17.7%. Type A AAD had higher mortality (33.8%) despite 75.3% undergoing surgery, while Type B AAD had 2.2% mortality with 76.1% receiving endovascular treatment.
  • Predictive factors for increased mortality included hypertension, Marfan syndrome, anterior chest pain, abdominal pain, migrating pain, and arch vessel involvement.

Conclusions:

  • This study provides a comprehensive overview of AAD clinical profiles and outcomes in China, highlighting significant differences between Type A and Type B dissections.
  • Hypertension emerged as a critical risk factor, emphasizing the importance of blood pressure control in AAD prevention and management.
  • The findings offer valuable data for clinicians in China for improved diagnosis, risk stratification, and treatment of acute aortic dissection.