Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 20, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Automatic shape-based level set segmentation for needle tracking in 3-D TRUS-guided prostate brachytherapy.

Ping Yan1, John C Cheeseborough, K S Clifford Chao

  • 1Department of Radiation Oncology, Columbia University, 622 W. 168th St., New York, NY 10032, USA.

Ultrasound in Medicine & Biology
|July 6, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

HERVOminer: a sequence similarity-based approach for recognizing endogenous retrovirus origin of the peptidome.

NPJ precision oncology·2026
Same author

Targeting PCK1 to overcome CDK4/6 inhibitor resistance for breast cancer therapy.

Cancer letters·2026
Same author

Heterologous prime-boost immunization of AAV-based neoantigen cancer vaccine induces anti-tumor immunity to inhibit tumor growth and relapse.

Cancer immunology, immunotherapy : CII·2026
Same author

Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy.

Cell death & disease·2026
Same author

Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer.

NPJ precision oncology·2026
Same author

Targeting DRP1 promotes radiotherapy-induced antitumor immunity via mitochondrial DNA-mediated cGAS-STING signaling in KRAS-mutated colorectal cancer.

Cancer letters·2025

This study introduces an automated tool for precise needle tracking during prostate brachytherapy using 3-D transrectal ultrasound (TRUS) images. The method significantly improves accuracy in localizing needle positions, crucial for effective early prostate cancer treatment.

Area of Science:

  • Medical Imaging
  • Computational Biology
  • Oncology

Background:

  • Prostate brachytherapy is a key treatment for early prostate cancer.
  • Accurate needle placement is critical for treatment efficacy.
  • Current methods for needle localization can be time-consuming and prone to error.

Purpose of the Study:

  • To develop and validate an automated, real-time needle tracking tool for 3-D transrectal ultrasound (TRUS) images.
  • To improve the precision and efficiency of needle placement during prostate brachytherapy.

Main Methods:

  • A shape-based level set segmentation tool was developed for needle tracking in 3-D TRUS images.
  • The tool utilizes shape information and level set techniques for real-time localization and endpoint estimation.

More Related Videos

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

Related Experiment Videos

Last Updated: May 20, 2026

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy
08:17

Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

Published on: June 7, 2015

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
09:11

Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy

Published on: April 9, 2019

  • Image acquisition involved a 2-D TRUS transducer and a computer-controlled stepper motor system.

    • Main Results:

    • The automated method achieved high accuracy, with differences within 0.1 mm for 17 of 19 implanted needles compared to expert segmentation.
    • Mean errors in automatic segmentation were within 0.25 mm when compared to the ground truth (expert CT segmentation).
    • The system demonstrated real-time TRUS-based needle placement accuracy within one pixel of manual expert segmentation.

    Conclusions:

    • The developed automated shape-based level set segmentation tool offers a highly accurate and efficient solution for real-time needle tracking in prostate brachytherapy.
    • This technology has the potential to enhance the precision and success rates of prostate brachytherapy procedures.
    • The validated accuracy supports its clinical applicability for improving treatment delivery.