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Updated: May 20, 2026
Compact Quantum Dots for Single-molecule Imaging
Published on: October 9, 2012
A facile and highly sensitive probe for Hg(II) based on metal-induced aggregation of ZnSe/ZnS quantum dots
1State Key Laboratory of Fine Chemical, School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, China.
Abstract:
Sensitive and selective detection strategies for toxic heavy metal ions, which are rapid, cheap and applicable to environmental and biological fields, are of significant importance. As a result of specific interaction between thiol(s) used as ligands and heavy metal ions, the photoluminescence intensity of quantum dots (QDs) in PBS buffer solution was quenched and the aggregation of QDs was formed at the same time. Herein, we present water-soluble, low toxic QDs, ZnSe/ZnS, which were applied for ultrasensitive Hg(2+) ion detection with a low detection limit (2.5 nM). In addition, a model has been proposed to explain the aggregation of QDs in the presence of heavy metal ions such as Hg(2+) ions.
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