Related Experiment Video
Updated: May 20, 2026
05:07
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Interatrial block - a novel risk factor for acute mesenteric ischemia.
Lovely Chhabra1, Indu Srinivasan, Pooja Sareen
1Department of Internal Medicine, Saint Vincent Hospital, University of Massachusetts Medical School, Worcester, MA 01608, USA. lovids@hotmail.com
Summary
Interatrial block (IAB), a delay in atrial conduction, was found in 88.9% of patients with acute mesenteric ischemia (AMeI). This high incidence suggests IAB may be a novel risk factor for AMeI.
Area of Science:
- Cardiology
- Gastroenterology
- Electrophysiology
Background:
- Interatrial block (IAB) is characterized by delayed conduction between the atria (P-wave duration ≥110 ms).
- IAB is associated with atrial arrhythmias, left atrial enlargement, left atrial electromechanical dysfunction, and cerebral thromboembolism.
- The relationship between IAB and acute occlusive mesenteric ischemia (AMeI) is not well-established.
Purpose of the Study:
- To investigate the incidence of IAB in patients diagnosed with acute occlusive mesenteric ischemia (AMeI).
- To determine if IAB is more prevalent in AMeI patients compared to general populations.
Main Methods:
- Retrospective review of medical records for patients admitted with AMeI between January 2009 and March 2011.
- Inclusion criteria: diagnosis of AMeI, exclusion of mechanical obstruction, non-occlusive ischemia, and venous thrombosis.
- Analysis of P-wave duration in electrocardiograms for patients in normal sinus rhythm without prior atrial arrhythmia history.
Main Results:
- Out of 342 reviewed patients, 172 met the criteria for AMeI.
- Among 99 patients in normal sinus rhythm with no prior atrial arrhythmia history, 88 (88.9%) exhibited IAB.
- This prevalence is more than double the reported average prevalence of IAB in general hospital populations (41% and 47%).
Conclusions:
- A significantly higher incidence of Interatrial Block (IAB) was observed in patients with acute occlusive mesenteric ischemia (AMeI).
- IAB may represent a novel risk factor for the development of AMeI, similar to its established role in embolic stroke.
- Further research is warranted to elucidate the pathophysiological link between IAB and AMeI.
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