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Genetic polymorphism of factor B of the complement system (Bf) in the Slovak population
D Staneková1, Z Starsia, M Niks
1Department of Microbiology and Immunology, Faculty of Medicine, Comenius University, Bratislava.
Folia Biologica
|January 1, 1990
Abstract:
The distribution of factor B (Bf) phenotypes and gene frequencies were investigated in 280 genetically unrelated persons of the Slovak population. Thin-layer agarose gel high-voltage electrophoresis and subsequent immunofixation were used. A low frequency of the "rare" allele BfFl was observed (BfFl = 0.0017). The frequencies of common Bf alleles BfS and BfF (BfS = 0.816, BfF = 0.1625) and a "rare" allele BfSO.7 (BfSO.7 = 0.0178) were inside the corresponding ranges of BfS, BfF and BfSO.7 found in European Caucasoids. No other variants were observed.