[Lidocaine in endotracheal intubation]

To evaluate the effect of lidocaîne use by IV during endotracheal intubation.

Our study was simple insu randomized prospective and comparative. It was done at the teaching hospital Gabriel Touré of Bamako from march to September 2005. Patients were distributed in 3 groups. The first group I: got fentanyl 2 nmg /kg+penthotal 5mg/kg+vecuronium 0.1mg/kg and intubation 3 mn later. The group II: lodocaîne 1,5mg +fentanyl 2nmg/kg+penthotal 5mg /kg + vecuronium 0.1mg/kg and intubation 3mn later. The group III: lodocaïne 1.5 mg/kg+pentothal 5mg/kg+vecuronium 0.1mg/kg and intubation 3 mn later.

The mean arterial pression to intubation has been 105.88±13.82 mmhg in the groupI, 96.60±15.01mmhg in the group II and 96.44±12.09mmhg in the group III with P = 0.008. To incision it has been 99.12±11.82 in the group I, 94.90 ±6.67 mmhg in the group II and 92.26±8.81 mmhg in the groupIII with P = 0.017.

Lidocaïne, used alone in Iv or associated to fentanyl 3 mn before intubation prevents hypertension related to intubation and incision.